Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling
نویسندگان
چکیده
منابع مشابه
Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling.
Cancer progression is associated with epigenetic alterations, such as changes in DNA methylation, histone modifications or variants incorporation. The p400 ATPase, which can incorporate the H2A.Z variant, and the Tip60 histone acetyltransferase are interacting chromatin-modifying proteins crucial for the control of cell proliferation. We demonstrate here that Tip60 acts as a tumor suppressor in...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2013
ISSN: 1460-2083,0964-6906
DOI: 10.1093/hmg/ddt604